Thanks guys for your quick help. Even if I did the complete reinstall procedure it was not necessary after all.
The reason for my problem seems to be a connected XBox Elite Gamepad. Even if I have numerous devices connected, which never caused a problem (Warthog Hotas, Saitek combat rudder pedals, Track IR) the gamepad seems to be the killer. Without everything works fine, plugged in and SB hangs in the loading screen forever. I think I have some homework to do in understanding the deeper Codemeter logics. But maybe you could also take something home, replicate my problem and warn some lazy guys who try to use a/this gamepad